Hi beep44ace,
If I am understanding your question correctly: you mean that which is the most dangerous microbial disease to plants. If so, my answer is that each plant species is different and host different pathogens that can significantly reduce crop production and in severe cases kill them before any food is formed. For example, wheat has septoria tritici blotch ,which can wipe out the whole wheat fields if resistant varieties and control measures are not taken. While barley is most suceptible to ramularia and rhyncosporium which do not infect wheat. Therefore, it is quite hard to find one most dangerous disease for all plant species.
ROOT-KNOT NEMATODES (MELOIDOGYNE SPP) infect many plant species, and they can be quite dangerous to plants in general.
Please feel free to ask, if you want more information.
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