• Question: why is not good if you are related to queen victoria?

    Asked by Hazel to Karen on 8 Nov 2016.
    • Photo: Karen

      Karen answered on 8 Nov 2016:


      Queen Victoria was a carrier of the gene for haemophilia. Haemophilia is a bleeding disorder that if is let untreated can cause those who have the disorder to bleed excessively and sometimes it can be fatal. The disorder is sexi-linked which means in the vast majority of cases women carry the gene but don’t have the disease and men who inherit the gene have the disease. This is because the gene for haemophilia is found on the X chromosome and women have 2 X chromosomes meaning that if the have one defective gene the other X chromosome will compensate with a normal gene. However men have only 1 X chromosome and 1 Y chromosome (Y is shorter than X) meaning that if they have a defective gene on X there is no other gene to compensate and therefore they have the disease.
      Meanwhile back to Queen Vic…she was a carrier, who had 9 children, 3 of whom were also carriers who married into different European royal families…Germany Russia and Spain and they passed the disease down through the bloodline to the male children who had the disease and the females who were carriers.
      The most famous of Queen Victoria’s affected descendants was Tsar Nicolas of Russias son Alexei. Alexei’s mother Alix (Queen Victoria’s granddaughter) was hugely under the influence of a monk named rasputin who claimed that he could cure Alexei with his healing powers. In fact he may well have helped him (Albeit inadvertently) as he instructed him to stop taking his medication, aspirin (which itself can cause bleeding) which doctors at the time gave him to help with his pain but unbeknownst to them made his bleeding worse. Because of his seemingly magic healing the Tsarina Alix gave him great power within the royal house and ultimately this may have contributed to the execution of the entire royal family by the Bolseviks.
      Haemophilia is therfore v often referred to as the royal disease due to its prevalence in European royal families…thanks to Queen Vic.
      Nowadays haemophilia can be treated v successfully by giving injections of the absent clotting factor (i.e. factor 8 or 9),.

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